Ondansetron Granules

(Product under development)
Ondansetron GranulesOndansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic (to treat nausea and vomiting), often following chemotherapy.

Its effects are thought to be on both peripheral and central nerves. Ondansetron reduces the activity of the vagus nerve, which deactivates the vomiting center in the medulla oblongata, and also blocks serotonin receptors in the chemoreceptor trigger zone.

It has little effect on vomiting caused by motion sickness, and does not have any effect on dopamine receptors or muscarinic receptors.

Available Form:
Ondansetron Granules
Ondansetron Pellets

Umang Pharmatech equipments used for production of Ondansetron Granules:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.


Ondansetron Granules
Systematic (IUPAC) Name
Ondansetron Granules
Identifiers
Ondansetron Granules
Chemical data
(RS)-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-2,3-dihydro-1H-carbazol-4(9H)-one
CAS number : 99614-02-5
ATC code : A04AA01
PubChem : CID 4595
DrugBank : APRD00481
ChemSpider : 4434
UNII : 4AF302ESOS
KEGG : D00456
ChEMBL : CHEMBL46
Formula : C18H19N3O
Mol. mass : 293.4 g/mol


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