Paroxetine Granules

(Product under development)
Paroxetine GranulesParoxetine (also known by the trade names Aropax, Paxil, Seroxat, Sereupin) is an SSRIantidepressant. Marketing of the drug began in 1992.

Paroxetine is used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, and generalized anxiety disorder in adultoutpatients.

In adults, the efficacy of paroxetine for depression is comparable to that of older tricyclic antidepressants, with fewer side effects and lower toxicity. Differences with newer antidepressants are subtler and mostly confined to side effects.

It shares the common side effects and contraindications of other SSRIs, with high rates of nausea, somnolence, and sexual side effects.

Unlike two other popular SSRI antidepressants, fluoxetine and sertraline, paroxetine is associated with clinically significant weight gain.

Pediatric trials of paroxetine for depression did not demonstrate statistical efficacy better than placebo and showed an increase in the risk of harmful outcomes, including episodes of self-harm and suicidal thoughts.

Discontinuing paroxetine is associated with a high risk of discontinuation or withdrawal syndrome. Due to the increased risk of birth defects, pregnant women or women planning to become pregnant are recommended to consult with their physician.

Available Form:
Paroxetine Granules
Paroxetine Pellets

Umang Pharmatech equipments used for production of Paroxetine Granules:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.

Paroxetine Granules
Systematic (IUPAC) Name
Paroxetine Granules
Identifiers
Paroxetine Granules
Chemical data
(3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine
CAS number : 61869-08-7
ATC code : N06AB05
PubChem : CID 43815
DrugBank : DB00715
ChemSpider : 39888
UNII : 41VRH5220H
KEGG : D02362
ChEMBL : CHEMBL490
Formula : C19H20FNO3
Mol. mass : 329.3


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