Sibutramine Granules

(Product under development)
Sibutramine GranulesSibutramine (usually in the form of the hydrochloride monohydrate salt) is an oral anorexiant. Until 2010 it was marketed and prescribed as an adjunct in the treatment of exogenous obesityalong with diet and exercise.

It has been associated with increased cardiovascular events and strokes and has been withdrawn from the market in countries and regions including Australia,Canada, China, the European Union (EU), Hong Kong, India, Mexico, Thailand, theUK, and the United States.

Sibutramine is a centrally-acting serotonin-norepinephrine reuptake inhibitor structurally related to amphetamines, although its mechanism of action is distinct.

It was sold under a variety of brand names including Reductil, Meridia and Sibutrex. It is classified as a Schedule IV controlled substance in the United States.

Available Form:
Sibutramine Granules
Sibutramine Pellets

Umang Pharmatech equipments used for production of Sibutramine Granules:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.

Sibutramine Granules
Systematic (IUPAC) Name
Sibutramine Granules
Identifiers
Sibutramine Granules
Chemical data
(±)-dimethyl-1-[1-(4- chlorophenyl) cyclobutyl]-N,N,3-trimethylbutan- 1-amine
CAS number : 106650-56-0
ATC code : A08AA10
PubChem : CID 5210
DrugBank : APRD00456
ChemSpider : 5021
UNII : WV5EC51866
KEGG : D08513
ChEMBL : CHEMBL1419
Formula : C17H26ClN
Mol. mass : 279.85 g/mol


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