Oestradiol Pellets

(Product under development)
Oestradiol PelletsEstradiol (E2 or 17β-estradiol, also oestradiol) is a sex hormone. Estradiol is abbreviated E2 as it has 2 hydroxyl groups in its molecular structure. Estrone has 1 (E1) and estriol has 3 (E3).

Estradiol is about 10 times as potent as estrone and about 80 times as potent as estriol in its estrogenic effect. Except during the early follicular phase of the menstrual cycle, its serum levels are somewhat higher than that of estrone during the reproductive years of the human female.

Thus it is the predominant estrogen during reproductive years both in terms of absolute serum levels as well as in terms of estrogenic activity. During menopause, estrone is the predominant circulating estrogen and during pregnancy estriol is the predominant circulating estrogen in terms of serum levels.

Estradiol is also present in males, being produced as an active metabolic product of testosterone. The serum levels of estradiol in males (8-40 pg/ml) are roughly comparable to those of postmenopausal women.

Estradiol "in vivo" is interconvertible with estrone; estradiol to estrone conversion being favored. Estradiol has not only a critical impact on reproductive and sexual functioning, but also affects other organs, including the bones.

Available Form:
Oestradiol Pellets
Oestradiol Granules

Umang Pharmatech equipments used for production of Oestradiol Pellets:
Drug Layering, Fluid Bed Dryer, Fluid Bed Coater, Sifter & Blender, Extruder and Twin spheronizer.


Oestradiol Pellets
Systematic (IUPAC) Name
Oestradiol Pellets
Identifiers
Oestradiol Pellets
Chemical data
(17β)-estra-1,3,5(10)-triene-3,17-diol
CAS number : 50-28-2
57-91-0 (±)
ATC code : G03CA03
PubChem : CID 5757
IUPHAR ligand : 1012
DrugBank : DB00783
ChemSpider : 5554
UNII : 4TI98Z838E
KEGG : D00105
ChEBI : CHEBI:16469
ChEMBL : CHEMBL135
Synonyms : (8R,9S,13S,
14S,17S)
-13-methyl
-6,7,8,9,
11,12,14,
15,16,17-decahydro-cyclopenta
[a]phenanthrene-3,17-diol
Formula : C8H6N4O5
Mol. mass : 238.16


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