Tramadol hydrochloride (Ultram, Tramal) is a centrally acting opioid analgesic, used in treating moderate to severe pain. The drug has a wide range of applications, including treatment for restless leg syndrome and fibromyalgia.
Tramadol possesses weak agonist actions at the μ-opioid receptor, releases serotonin, and inhibits the reuptake of norepinephrine.
Tramadol is a synthetic analog of the phenanthrene alkaloid codeine and, as such, is an opioid and also a prodrug (codeine is metabolized to morphine, tramadol is converted to O-desmethyltramadol). Opioids are chemical compounds which act upon one or more of the human opiate receptors.
The euphoria and respiratory depression are mainly caused by the μ1 and μ2 receptors; the addictive nature of the drug is due to these effects as well as its serotonergic/noradrenergic effects . The opioid agonistic effect of tramadol and its major metabolite(s) are almost exclusively mediated by the substance's action at the μ-opioid receptor.
This characteristic distinguishes tramadol from many other substances (including morphine) of the opioid drug class, which generally do not possess tramadol's degree of subtype selectivity.
|Tramadol Pellets Systematic (IUPAC) Name||Tramadol Pellets Identifiers||Tramadol Pellets Chemical data|
We supply Tramadol in pellets form and granules form. Our Tramadol Pellets can be used in a variety of Pharmaceutical applications like It can be used in tablets and capsules.
We also offer Sustained Release(SR) / Immediate Release (IR) and Enteric Coated (EC) Tramadol Pellets.
Umang pharmatech has the capability to manufacture Tramadol Pellets of various particle sizes.